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Framingham Risk Calculator Canada . The frs estimates the 10 year risk of manifesting clinical cvd (cad, stroke, pvd, chf, cardiac death). Criteria for diagnosing familial hypercholesterolemia. Framingham Risk Score Amtframe.co from amtframe.co The formula uses age, gender, total cholesterol, hdl cholesterol, and. The formula is based on the framingham heart study. Us data, 10 year risk heart attacks + angina/coronary insufficiency + heart failure + strokes + intermittent claudication.